Moji Christianah Adeyeye, Ph.D.
Professor of Pharmaceutics

441 Mellon Hall
T 412.396.5133
E adeyeyechri@duq.edu

Institution/Location	Degree	Year
University of Nigeria, Nsukka, Nigeria	B.S	1976
Pharmaceutics, University of Georgia, Athens, GA, USA	M.S	1985
Pharmaceutics, University of Georgia, Athens, GA, USA	Ph.D	1988

• 2009 - Visiting Professor, Nnamdi Azikwe University, Awka, Anambra State, Nigeria
• 2008 - Chair-Elect, American Association of Pharmaceutical Scientists (AAPS) Membership Strategic Oversight Committee
• 2008 - J. William Fulbright Senior Specialist
• 2006 - Adjunct Professor, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Lagos, Lagos, Nigeria
• 2004-2005 - Senior Fulbright Scholar, Faculty of Pharmacy, University of Lagos, Idi-Araba, Lagos and National Institute for Pharmaceutical Research and Development, Abuja, FCT
  Project: African Area AIDS Research: Quality Assurance and Bioequivalence of Anti-retroviral Drugs
• 2004 - President, Drugs for AIDS and HIV Patients (DAHP) – a faith based tax-exempt organization. USA)
  Project: Prevention of HIV/AIDS among Youths, Prevention of Mother-to-child Transmission and Care for Orphans and Vulnerable Children
• 2003 – Professor of Pharmaceutics and Pharmaceutical Technology, Division of Pharmaceutical Sciences, School of Pharmacy, Duquesne University, Pittsburgh, PA, USA
• 2002-2004 - Chair, AAPS Preformulation Focus Group
• 1999-2004 - President, Nigerian Association of American Pharmaceutical Scientists
• 1994-2002 - Associate Professor of Pharmaceutics, Duquesne Pittsburgh, PA, USA
• 1988-1989 - Visiting Associate Professor, Department of Pharmaceutics, School of Pharmacy University of Washington, Seattle, WA
• 1994-1996 - Adjunct Assistant/Associate Professor, Department of Pharmacology, School of Medicine, University, of Pittsburgh, Pittsburgh, PA
• 1989-1994 - Assistant Professor, Duquesne University, Pittsburgh, PA
• 1988-1989 - Assistant Professor, School of Pharmacy, University of Pueto Rico, San Juan, PR
• 1976-1980 - Pharmacist, University College Hospital, Ibadan, Oyo State, Nigeria
• 1979-1980 - Head of Pharmacy, Baptist Hospital, Ogbomoso, Oyo State, Nigeria

Honors and Awards

• 2009 J. William Fulbright Senior Specialist Candidate, Obafemi Awolowo University, Ile-Ife, Nigeria
• 2008 Fellow, American Association of Pharmaceutical Scientists (AAPS)
• 2008 Duquesne University Presidential Award for Excellence in Service to the Mission
• 2008 Award for Excellence in Service, School of Pharmacy, Duquesne University
• 2006- J. William Fulbright Senior Specialist Candidate
  
• 2004-2005 J. William Fulbright Scholar Award for African Regional Research Program on AIDS and AIDS-Related Research
  
• 2003 Duquesne University Presidential Award for Excellence in Scholarship
  
• 2001, 2003 Award for Excellence in Scholarship, School of Pharmacy, Duquesne University
  
• 2003 Award for Excellence in Scholarship, Division of Pharmaceutical Sciences, Duquesne University 
  
• 1998 Recognition: Focus Group Member: Capsugel Expert System for Development of Hard Gelatin Capsule Dosage Form
  
• 1991/1992 Marquis Who is Who of American Women
  
• 1985/1986 Award for Excellence for Research Program by a Graduate student, School of Pharmacy, University of Georgia
  
• 1983 Graduate Fellowship, American Association of University Women (AAUW)

Courses Taught: [Professional (P) and Graduate (G)]

• Pharmaceutic Principles and Drug Delivery Systems (P)
• Dosage Formulation and Development – Preformulation, Modified Release Technology, Excipients, etc. (G)
• Manufacturing Pharmacy – FDA Current Good Manufacturing Practices, Solid Dosage Form Manufacturing, Equipment Cleaning Validation, etc. (G)
• Pharmaceutical Unit Processes – Processes used in Solids Development (G)
• Pharmaceutical Unit Processes - Processes used in Liquids Development (G)
• Advanced Pharmaceutics (G)
• Independent Research (P) (G)
• M.S. Thesis (G)
• Ph.D. Dissertation (G)
• Graduate Seminar (G)

Research Interests

Preformulation

• Early Phase Solid and Liquid State Characterization
• Drug and Excipient Characterization
• Forced Degradation
• Analytical Method Development

• Apoptosis and Cancer
• Blood brain barrier and drug transport

Publications

Books (Total = 2)

1. Adeyeye, Moji: Out of Mouths of Children and What Adults (Everyone) Should Know About HIV/AIDS. Book Craft Publisher, Ibadan, Nigeria. 2005: ISBN 978203056-2

2. Preformulation in Solid Dosage Form Development, Eds. Moji Christianah Adeyeye and Harry G. Brittain. Informa Healthcare Publisher. 2008. ISBN: 9780824758097

Book Chapters (Total = 5)

3. Christianah Moji Adeyeye and Pui-Kai Li. Diclofenac Sodium (Non steroidal anti-inflammatory drug): in Analytical Profile of Drug Substances, (Ed. K. Florey] Academic Press, 19, 123-144 (1991) ISBN: 0-12-2608194

4. Christianah Moji Adeyeye and Eugene Barabas, Polyvinylpyrrolidone (Povidone). Analytical Profiles of Drug Substances and Excipients, (Ed. H. Brittain) Academic Press, 22, 555 - 686 (1993) ISBN: 0-12-260822-4

5. Eugene Barabas and Christianah Moji Adeyeye, Crospovidone, Analytical Profiles of Drug Substances and Excipients, (Ed. H. Brittain), Vol. 24, Academic Press (1996) ISBN:0-12-260824-0

6. Moji Christianah Adeyeye, Use of Chiral Excipients in Enantiomeric Formulations in Chirality in Drug Design and Development. Eds: Indra Reddy and Reza Mehvar. Marcel Dekker Inc. Publisher: ISBN:0-8247-5062-4

7. Drug-Excipient Interaction during Solid Dosage Form Development in Preformulation in Solid Dosage Form Development, Eds. Moji Christianah Adeyeye and Harry G. Brittain. Informa Healthcare Publisher. 2008. ISBN: 9780824758097

Research Articles

8. Beatrice Nkem Chukwumezie, Mark Wojcik, Paul Malak and Moji Christianah Adeyeye, Feasibility Studies in Spheronization and Scale-up of Ibuprofen Microparticulates Using the Rotor Disk Fluid-bed Technology. PharmSci. Tech. 2002; 3(1) Article 2, 1-13. http://www.aapspharmscitech.org

9. Christianah Moji Adeyeye, Ashwinkumar Jain, Mohamed K. Ghorab and William J. Reilly, Viscoeleastic Evaluation of Hydrocortisone Topical creams Containing Microcrystalline Cellulose/Sodium Carboxymethyl Cellulose (Avicel® CL-611) as Stabilizer. PharmSci. Tech. 2002; 3(2) Article 7, 1-10. http://www.aapspharmscitech.org

10. Ashwinkumar Jain, Bruce Aungst and Moji Christianah Adeyeye, In-vivo/In-vivo Evaluation of Buccal Tablets Prepared Using Danazol-Sulfobutylether-?-Cyclodextrin 7 (SBE 7) Complexes J. Pharm. Sci. 91(7): 1659-1668 (2002)

11. Mohamed Ghorab and Moji Christianah Adeyeye, Enhanced bioavailability of Process-Induced fast Dissolving Ibuprofen Co-granulated with ?-Cyclodextrin, J. Pharm. Sci., 92(8), 2003

12. Beatrice Nkem Chukwumezie, Mark Wojcik, Paul Malak, Frank D’Amico and Moji Christianah Adeyeye, Factorial Design in the Spheronization of Ibuprofen Microparticulates Using Rotor Disk Fluid-Bed Technology, Pharm. Development and Technol. Vol. 9(1), pp. 49-62, 2004

13. John P. Gibbs, Moji Christianah Adeyeye, Ziping Yang and Danny D. Shen, Valproic Acid Uptake by Bovine Brain Microvessel Endothelial Cells: Role of Active Efflux Transport. Epilepsy Research, 58 (2004) pp. 53-66

14. Adeyeye, MC; Mwangi, E.; Katondo, B.; Jain, A.; Ichikawa, H.; Fukumori, Y. JN: Dissolution Stability studies of suspensions of Prolonged-release Diclofenac Microcapsules Prepared by the Wurster Process: I. Eudragit-based Formulation and Possible Drug-excipient Interaction. Journal of Microencapsulation PD: June 2005 Vol: 22 NO: 4 PG: 333-342

15. Adeyeye, MC; Mwangi, E., Fujioka, K; Ichikawa, H., Fukumori, Y., Dissolution Stability Studies of Suspensions of Prolonged-release Diclofenac Microcapsules Prepared by the Wurster Process II, Improved Dissolution Stability. Journal of Microencapsulation. Vol: 22 NO: 4, 343-353, 2005

16. Vishal Bijlani, Domotiere Yuonayel, Sabitha Katpally, Beatrice Nkem Chukwumezie, and M. C. Adeyeye, Monitoring Ibuprofen Release from (Avicel-based) Multi-particulates: In-situ Fiber Optic Technique versus the HPLC Method. A Technical Note. AAPS PharmSciTech, 2007; 8 (3) Article 52 (http://www.aapspharmscitech.org)

17. Mohamed K. Ghorab and Moji Christianah Adeyeye. High Shear Mixing Granulation of Ibuprofen and ?-Cyclodextrin: Effects of Process Variables on Ibuprofen Dissolution. AAPS PharmSciTech 2007; 8 (4) Article 84 (http://www.aapspharmscitech.org).

Patents

1. Christianah Moji Adeyeye, Hideki Ichikawa and Yoshinobu Fukumori,, Method of Treating a Patient with a Prolonged Time-Release Drug and the Drug Itself, U.S. Patent No. 6,156,340, December 5, 2000

2. Christianah Moji Adeyeye and Ashwin Jain, Controlled Release Pharmaceutical Preparation for Treatment of Endometriosis and Fibrocystic Breast Disease., U.S. Patent No. 6, May, 2003

Patent Pending

3. Anti-retroviral Drug Formulations for Treatment of Children Exposed to HIV/AIDS. PCT/US2009/031285. Patent Pending

Extra Mural Funding

Selected Grant Awards

Consultancy

• Whitehall Robbins Consumer Health (WYETH Consumer Health), NJ
• Albemarle Corporation, Baton Rouge, Louisiana
  Penwest, Patterson, NY
• Trutek Corporation, Somerville, NJ
• Bain & Company Inc., UK, through Intellectexchange, Inc.
• Retainership
  • Expert Opinion Documentation
  • Deposition

Service (Partial List) DUQUESNE UNIVERSITY

2007 - University Diversity Council

2004-2005 - President’s Faculty Awards for Excellence Committee

SCHOOL OF PHARMACY

2007 - Chair - Graduate School of Pharmaceutical. Sciences Curriculum Committee The committee developed a set of working guidelines for the development, assessment of courses taught at the graduate level

2007 - 2008 - Member - Graduate School of Pharmaceutical. Sciences Council

2006 - 2007 - Member - Graduate School Review/Self-Study Committee

2006 – 2007 - Chair - Graduate School Review - Adequacy of Resources Sub-committee

2006 - Chair - Graduate School by Laws Committee Chair

2002 - Member - School of Pharmacy Faculty Excellence Award Committee

2002 - Faculty Patron of Duquesne University Student National Pharmaceutical Association (SNPhA)

Service in National Associations (Partial List)

2008 - Chair-Elect, MSOC, Association of American Pharmaceutical Scientists (AAPS)

2007 - Chair, Qualification Sub-Team, MSOC, Association of American Pharmaceutical Scientists

2006 - Member of Board, Nigerian Association of Pharmacists and Pharmaceutical Scientists in the Americas (NAPPSA)

2006 - 2007 - AAPS’s PDD/PT Section – Mission and Vision Committee
The mission of the PDD Section is to serve its membership and the public by fostering basic and applied research within the discipline of pharmaceutics and drug delivery and pharmaceutical technology

2004 - 2007 - Member, Strategic Oversight Committee (MSOC), AAPS
The charge is to examine the benefits being provided by the Association to its membership and provide recommendations for improvement

2004 - President, Drugs for AIDS and HIV Patients (DAHP) – a faith based tax-exempt organization. USA); Registered NGO in Nigeria
Project: Prevention of HIV/AIDS among Youths, Prevention of Mother-to-child Transmission and Care for Orphans and Vulnerable Children

2002 - 2004 - Chair, AAPS Preformulation Focus Group

2000 - 2004 - Member, Impurities Working group of AAPS/FDA/Product Quality Research Initiatives (PQRI)

2002 - Member of the planning committee: AAPS First Annual Pharmaceutics and Drug Delivery Conference, Crystal Gateway Marriott, Arlington, VA

Global Community

Motivated by Duquesne University’s DU More…initiative and commitment to contribute toward the fight against HIV/AIDS in Africa, I founded an organization - Drugs for AIDS and HIV Patients (DAHP). I reach out internationally through programs that focus on prevention education, care and treatment of HIV/AIDS children, especially orphans and vulnerable children (OVC) in Nigeria. DAHP’s activities include the following:

Prevention Awareness and Education

• HIV/AIDS awareness and prevention education to high school children in the Southwest of Nigeria (over 5000 children in 8 schools)
• Publication of a book on HIV/AIDS awareness and prevention in 2005, targeted at high school children. The title is “Out of the Mouths of Children…and What Adults Should Know about HIV/AIDS.
• Prevention-of-mother-to-child transmission (PMTCT) of HIV/AIDS (funded Caesarean section or guided normal delivery of over 35 babies)

• Conduct workshops and campaign in schools, churches and the local communities
• Screening of people including children for HIV (screened approximately 10,000)
• Monitors the response to treatment (CD4) of patients

• Our newest initiative-SAVE-A-CHILD or S.A.C is targeted toward HIV/AIDS orphans. It was birthed in March 2006 but launched in December 2007 at Duquesne University. It grew as a result of the starving, lack of care and later loss of two children among the ones we serve in Nigeria. S.A.C. is a christened name given by a church friend for the burden and passion that she and DAHP have for children
• DAHP takes care of 20 OVC through provision of food, clothing, school supplies and supplementing transportation costs of the parents to collect their drugs. We have a total of about 60 children
• An Extended Family Home (Sarah’s Home) for orphan and most vulnerable children in the group was started in early 2006 in Nigeria. The Extended Home also serves as after School Day Care and Play Center for other kids and will be used as a training center for mothers or women (80-90% of whom are widows)

• Supplementation of transportation costs to travel to another city where the drugs are provided by the government
• Home care (visitation) to families affected or living with HIV/AIDS

• American Association of Pharmaceutical Scientists (AAPS)
• American Association of University Professors (AAUP)
• American Pharmaceutical Association (APhA)
• American Association of Colleges of Pharmacy (AACP)
• International Society of Pharmaceutical Engineers (ISPE)
• Controlled Release Society (CRS)
• Nigerian Association of Pharmacists and Pharmaceutical Scientists in the Americas (NAPPSA)
• International Pharmaceutical Excipients Council of the Americas (IPEC Americas)