B.S. (Pharmacy)--Duquesne University
Ph.D.(Pharmaceutics)--University of Kentucky
Research Program
My research is focused on the development and
validation of near-infrared spectroscopic methods
and equipment for nondestructive analysis of pharmaceuticals.
Current projects include the development of methods
for monitoring mixing of powders and semisolids
and the coating of tablets and granules. Research
support is obtained primarily from industrial
sponsors, providing opportunities for students
to participate in industrial projects.
Graduate students are usually supported through
fellowships or as research assistants. Teaching
assistantships may be available through the Graduate
School of Pharmaceutical Sciences. Opportunities
for research experience are available for undergraduates
in pharmacy or chemistry.
A wide variety of near-infrared
instrumentation is available in the laboratory
for graduate research. Results of the work carried
out in Dr. Drennen's laboratory are routinely
presented at the Pittsburgh Conference, annual
meetings of the American Association of Pharmaceutical
Scientists, the biannual International Diffuse
Reflectance Conference (Chambersburg, PA) and
the Eastern Analytical Symposium (Somerset, NJ).
Select Publications
- Dr. James K. Drennen, III, co-authored the book
"Pharmaceutical and Medical Applications of Near-Infrared
Spectroscopy" with Emil W. Ciurczak published
by Marcel Dekker in the Practical Spectroscopy
Series (Volume 31)
- James K. Drennen and John
D.Kirsch, "Nondestructive tablet hardness testing
by near-infrared spectroscopy: a new and robust
spectral best-fit algorithm," Journal of Pharmaceutical
and Biomedical Analysis, 19(1999) 351-362.
- David A. Wargo and James
K. Drennen, "Near-Infrared Spectroscopic Characterization
of Pharmaceutical Powder Blends," Journal of Pharmaceutical
and Biomedical Analysis, 14 (1996), 1415-1423.
- John D. Kirsch and James K. Drennen, "Near-Infrared
Spectroscopic Monitoring of the Film Coating Process,"
Pharmaceutical Research, 13(2), 234-237 (1996).
- Nadhamuni G. Nerella and
James K. Drennen, "Depth-Resolved Near-Infrared
Spectroscopy," Applied Spectroscopy, 50(3), 285-291
(1995).
- John D. Kirsch and James
K. Drennen, "Determination of Film-Coated Tablet
Parameters by NIR Spectroscopy," Journal of Pharmaceutical
and Biomedical Analysis, 13(1995), 1273-1281.
- John D. Kirsch and James
K. Drennen, "Near-Infrared Spectroscopy: Applications
in the Analysis of Tablets and Solid Pharmaceutical
Dosage Forms," Applied Spectroscopy Reviews, 30(3),
139-174 (1995).
Presentations
Chaired a symposium on calibration Transfer at
the IFPAC-2004 Conference and presented the following
two invited lectures: Calibration Transfer: A
Pharmaceutical Case Study and PAT Implementation
– Integrating Fundamental Sciences Information
case study.
Graduate Students or
Post-Doctoral Fellows
Potential students or post-doctoral candidates
interested in working with Dr. Drennen's research
group should send E-mail, call or write to:
Dr. James K. Drennen
Graduate School of Pharmaceutical Sciences
Duquesne University
Pittsburgh, PA 15282
Students with backgrounds
in pharmacy, chemistry and chemical engineering
are ideally suited to pursue graduate studies
in pharmaceutics/pharmaceutical analysis. Opportunities
in Dr. Drennen's research group may be available
for those students with backgrounds in physics,
computer science or electrical engineering as
well.
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