David J Lapinsky, Ph.D.
Assistant Professor of Medicinal Chemistry

422B Mellon Hall
T 412.396.6069
L 412.396.1973 (450 Mellon Hall)
F 412.396.5593
E lapinskyd@duq.edu

B.S.(Pharmacy)--Duquesne University
Ph.D. -- The Ohio State University

• Ring E analogs of methyllycaconitine (MLA) as novel nicotinic antagonists. S.C. Bergmeier, D.J. Lapinsky, R.B. Free, and D.B. McKay; Bioorganic & Medicinal Chemistry Letters 1999, 9, 2263-2266.
  
• A Suzuki cross-coupling route to substituted aziridines. D.J. Lapinsky and S.C. Bergmeier; Tetrahedron Letters 2001, 42, 8583-8586.
  
• Structure-activity studies with ring E analogues of methyllycaconitine on bovine adrenal α3β4* nicotinic receptors. D.L. Bryant, R.B. Free, S.M. Thomasy, D.J. Lapinsky, K.A. Ismail, S.B. McKay, S.C. Bergmeier, and D.B. McKay;
  
• Neuroscience Research 2002, 42, 57-63.
  
• Effects of methyllycaconitine and related analogues on bovine adrenal α3β4* nicotinic acetylcholine receptors. D.L. Bryant, R.B. Free, S.M. Thomasy, D.J. Lapinsky, K.A. Ismail, K.M. Arason, S.C. Bergmeier, and D.B. McKay; Annals of the New York Academy of Sciences 2002, 971, 139-141.
  
• Aziridine-allylsilane-mediated synthesis of exocyclic γ-amino olefins and azabicyclo[x.y.1]-systems. D.J. Lapinsky and S.C. Bergmeier; Tetrahedron 2002, 58, 7109-7117.
  
• Studies in aziridine-allylsilane chemistry: Extension of Scope. D.J. Lapinsky; Dissertation, 2002, The Ohio State University.
  
• Substitution effects in intramolecular aziridine-allylsilane cyclizations. D.J. Lapinsky, A.B. Pulipaka, and S.C. Bergmeier; submitted to J. Org. Chem. 2/2008.
  
• Chapter 3: Three-membered ring systems. S.C. Bergmeier and D.J. Lapinsky; Progress in Heterocyclic Chemistry 2008, 20, submitted 3/2008.

• Isosteric replacement of bisphosphonates in the development of myo-inositol monophosphatase inhibitors. D.J. Lapinsky, D. Gaitonde, and M.W. Harrold; 18th Annual Undergraduate Research Seminar, Oral Presentation, West Virginia University, 11 / 1996.
  
• Ring E analogs of methyllycaconitine (MLA) as novel nicotinic antagonists. S.C. Bergmeier, D.J. Lapinsky, R.B. Free, and D.B. McKay; 36th National Organic Chemistry Symposium, Poster #148, University of Wisconsin-Madison, 6 / 1999. 4
  
• Ring E analogs of methyllycaconitine (MLA) as novel nicotinic antagonists. S.C. Bergmeier, D.J. Lapinsky, R.B. Free, and D.B. McKay; 32nd Graduate Student Symposium in Medicinal Chemistry, Poster, SUNY at Buffalo, 6 / 1999.
  
• Synthesis of azabicyclo[x.2.1]-systems using an intramolecular aziridineallylsilane cyclization reaction. D.J. Lapinsky and S.C. Bergmeier; 37th National Organic Chemistry Symposium, Poster #115, Montana State University, 6 / 2001.
  
• Synthesis of azabicyclo[x.2.1]-systems using an intramolecular aziridineallylsilane cyclization reaction. D.J. Lapinsky and S.C. Bergmeier; 34th Graduate Student Symposium in Medicinal Chemistry, Oral Presentation, Ohio State University, 6 / 2001.

• PHBMS 425: Endocrine Module
  GPHSC 691: Medicinal Chemistry Seminar I
  

Spring Semester 2008

• PHBMS 423: GI / Rheumatology Module
• GPHSC 527: Advanced Medicinal Chemistry
  
• GPHSC 623: Selected Topics in Medicinal Chemisty

• CHEM 211 & 212: Organic Chemistry I & II
  
• CHEM 251& 252: Honors Organic Chemistry I & II
  
• CHEM 442 & 443: Principles of Medicinal Chemistry I & II
  
• CHEM 352: Introductory Module in Experimental
• Chemistry II (Organic Synthesis)
  
• CHEM 374: Advanced Module in Synthetic Organic Chemistry
  
• CHEM 384: Advanced Module in Instrumental Analysis
  
• CHEM 401 & 562: Advanced Organic Chemistry I & II

• Duquesne University School of Pharmacy Committees
  Pharmacy Safety
  
• Pharmacy Faculty Excellence Award
  
• Duquesne University Student Organizations: Faculty Advisor
  
• Graduate Student Association (GSA)